Search For "t cell"
Researchers reveal how ammonia dysregulates T cell function
Updated : 3 years, 2 months ago IST
According to new research, mice with colorectal cancer who have tumours with high levels of ammonia have fewer T cells and are less responsive to immunotherapy. Ammonia, which is crucial for anti-tumor immunity, has been demonstrated to impede the proliferation and operation of T cells.
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Study unveils strategy to enhance immune response to viral infections
Updated : 3 years, 2 months ago IST
The immune system, including T cells, is known to be compromised by severe viral infections and cancer, a condition known as immunological 'exhaustion'. The development of novel medicines for cancer or severe viral infections has a major focus on overcoming immunological fatigue.
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High levels of ammonia in colon cancer restrict T cell development: Resear
Updated : 3 years, 2 months ago IST
The researchers discovered, ammonia inhibits the growth and function of T cells, which are essential for anti-tumour immunity.
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Researchers unravel population of 'cheating' cells in cancers
Updated : 3 years, 2 months ago IST
Researchers at UConn Health, Yale, and Johns Hopkins have identified that some cancer cells can "cheat" by escaping constraints imposed by lack of oxygen, allowing the cancer cells to continue to grow.
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Research: Killing pancreatic cancer with T cells that supercharge themselv
Updated : 3 years, 2 months ago IST
Scientists at UC San Francisco (UCSF) have engineered T cells to produce a potent anti-cancer cytokine, but only when they encounter tumour cells.
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Experimental cancer therapy shows 73 pc success rate in trials: Study
Updated : 3 years, 3 months ago IST
The treatment, which is referred to as a "bispecific antibody," binds to both T cells and multiple myeloma cells and instructs the T cells, which are white blood cells that can be used to fight off diseases
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Evidence of autoimmunity's origins uncovered via new approach: Study
Updated : 3 years, 3 months ago IST
A study supports the idea that some T cells that react to microbes also may react to normal human proteins, causing autoimmune disease. The findings promise to accelerate efforts to improve diagnostic tools and treatments for autoimmune diseases.
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Study finds how Immune cells in ALS patients can predict disease
Updated : 3 years, 3 months ago IST
It is possible to determine how quickly the disease might advance by detecting immune cells in the cerebrospinal fluid after diagnosing ALS, according to researchers.
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Study: CAR T cell therapy reaches beyond cancer
Updated : 3 years, 3 months ago IST
Engineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can do to fight blood cancers. Now, investigators have reported highly promising early results for CAR T therapy in a small set of patients with the autoimmune disease lupus. Penn Medicine C
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Researchers develop promising new cancer therapy
Updated : 3 years, 3 months ago IST
Immune checkpoint inhibitors such as Keytruda and Opdivo work by unleashing the immune system's T cells to attack tumour cells. Their introduction a decade ago marked a major advance in cancer therapy, but only 10 per cent to 30 per cent of treated patients experience long-term improvement.
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Research finds unique genetic signatures in different types of cancer
Updated : 3 years, 4 months ago IST
A recent research has identified a unique genetic signature among subsets of infiltrating T cells of different types of cancer after analyzing data from a public repository, CD4-T, CD8-T cells, and Treg.
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Narayana Health initiates Phase II Clinical Trial of CAR-T
Updated : 3 years, 4 months ago IST
Bengaluru (Karnataka) [India], October 20 (ANI/NewsVoir): Narayana Health, one of the leading healthcare chain in India, today announced that they have offered support to Immuneel Therapeutics, to build the most advanced CAR-T cell laboratory at the Narayana Health city Bengaluru. With this
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