Epilepsy affects 4 per cent of the population and is one of the most common brain disorders among children. Most seizure recurrences can be avoided with modern medicine, but approximately 20 per cent of patients do not respond to treatment.
A new atlas maps more than 300 protein kinases found in human cells and identifies which types of protein substrates they target. The atlas could help scientists understand what happens when cells become cancerous or are treated with specific drugs.
A study is providing a glimpse into dinosaur and bird diversity in Patagonia during the Late Cretaceous, just before the non-avian dinosaurs went extinct. The fossils represent the first record of theropods, a dinosaur group that includes both modern birds and their closest non-avian dinosau
Northwestern University-led researchers have created the first highly mature neurons from human induced pluripotent stem cells (iPSCs), a feat that opens new opportunities for medical research and potential transplantation therapies for neurodegenerative diseases and traumatic injuries.
The Martian meteorite Tissint contains a huge diversity of organic compounds, found an international team of researchers led by Technical University of Munich and Helmholtz Munich's Philippe Schmitt-Kopplin and including Carnegie's Andrew Steele. Their work is published in Science Advances.
Researchers from the Johns Hopkins University School of Medicine and Bloomberg School of Public Health have significantly added to evidence that social isolation is a significant risk factor for dementia in community-dwelling (noninstitutionalized) older adults in two studies using nationall
This migration mode is one of the ways cancer cells navigate tissue during metastasis. In a new study researchers have explored mesenchymal migration through cell simulations and mathematical modeling. Their aim: to learn more about how cancer cells size up surrounding tissue for stiffness a
Researchers have uncovered a series of molecular interactions that may be crucial in preventing the spread of cancer cells. There is currently no effective therapeutic strategy to stop metastasis, which is the main cause of death from solid malignant tumours.
A significant increase in the risk of dementia and Alzheimer's disease is associated with various cardiometabolic disorders, such as diabetes, heart disease, and stroke. Researchers from the Karolinska Institutet have recently conducted a twin study that raises the possibility that dementia
Researchers have discovered how to modify the function of an enzyme crucial to fat production in fruit flies, which could lead to more effective treatments for cancer and childhood obesity in humans.
Researchers found that neuroimaging technology has great promise in assisting clinicians in the identification of specific symptoms of mental health disorders that are associated with abnormal patterns of brain activity.
A new study at Washington University School of Medicine in St. Louis may help explain how excess weight can contribute to diabetes and may provide researchers with a target to help prevent or delay diabetes in some of those at risk.