Search For "mutation"
Genetic mutations direct immune defences in leukaemia linked rare bone mar
Updated : 2 years, 8 months ago IST
A discovery that may result in novel medicines to halt or reverse the disease could be beneficial to patients with a rare genetic bone marrow problem who are at an elevated risk of blood malignancies.
Read More
Researchers discover jumping genes can lead to rare syndrome in children
Updated : 2 years, 9 months ago IST
The activation of certain genes known to cause the uncommon illness MSL3 syndrome in children is regulated by a novel family of DNA elements.
Read More
Cause, cure identified for common type of high blood pressure: Study
Updated : 2 years, 9 months ago IST
One out of every twenty persons with hypertension has a small benign nodule as the root cause. Aldosterone, a hormone that the nodule generates, regulates the body's salt levels. A gene mutation found in some of these nodules that causes a significant, sporadic overproduction of the hormone
Read More
Study finds cause and cure for common type of high blood pressure
Updated : 2 years, 9 months ago IST
Researchers discovered a gene mutation that causes a common type of hypertension (high blood pressure) and a treatment for it. This study was published in the journal, 'Nature Genetics.'
Read More
Older trees accrue more mutations than their younger ones: Study
Updated : 2 years, 9 months ago IST
Older, long-lived trees are thought to contribute more to the creation and maintenance of genetic diversity than young, short-lived trees, according to research on the relationship between the growth rate of tropical trees and the frequency of genetic mutations they accumulate.
Read More
Researchers suggest effects of genetic mutations on RNA formation
Updated : 2 years, 9 months ago IST
A Munich-based research team developed an algorithm that predicts the consequences of genetic changes on RNA production six times more accurately than earlier models. As a result, the genetic origins of uncommon hereditary disorders and cancer may now be more precisely identified.
Read More
Study predicts the effects of genetic mutations on RNA formation
Updated : 2 years, 9 months ago IST
A research team from Munich has created an algorithm that predicts the effects of genetic mutations on RNA formation six times more precisely than previous models. As a result, the genetic causes of rare hereditary diseases and cancer can now be pinpointed with greater accuracy.
Read More
Study shows healthy kidneys despite high blood pressure
Updated : 2 years, 9 months ago IST
Scientists found that unless you happen to have a PDE3A gene mutation, high blood pressure eventually damages the kidneys. According to research published in 'Kidney International' by a team led by Enno Klussmann of the Max Delbruck Centre and the DZHK, a mutation that causes severe hyperte
Read More
Study illustrates how cells choose DNA repair methods
Updated : 2 years, 9 months ago IST
DNA is usually regarded as the blueprint for life and is essential for an organism to perform biological tasks. A range of factors, including radical metabolites, radiation, and other hazardous substances, can cause DNA damage. Because DNA is a two-stranded molecule, it can be damaged on eit
Read More
Study reveals how cells select DNA damage repair pathways
Updated : 2 years, 9 months ago IST
DNA is widely recognized as the blueprint for life, and it is required for an organism to assist biological functions. DNA may be damaged by a variety of circumstances, including radical metabolites, radiation, and some toxic compounds. Because DNA is a two-stranded molecule, any one or both
Read More
Gene mutations responsible for rare illness causing heart attack in youngs
Updated : 2 years, 10 months ago IST
The findings, published in late April in Circulation, suggest that treatments could be developed to manage the condition rather than requiring a heart transplant, which is the standard treatment for this condition in children.
Read More
Researchers discover how DNA repair can go wrong and lead to disease
Updated : 2 years, 10 months ago IST
"DNA breaks and repair events occur thousands of times per day in each of us," said Freudenreich. "Most of the time, repair works the way it should. But we now have a better understanding of how things can go wrong, and we can apply this knowledge to new therapeutic strategies."
Read More