Search For "mice"
Do you know time restricted eating affects gene expression in areas of bod
Updated : 3 years, 2 months ago IST
Time-restricted eating has been shown in studies to have health benefits, including an increase in life span, making practises like intermittent fasting a hot topic in the wellness industry. However, how it affects the body at the molecular level and how those changes interact across multipl
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Research: Potential new targets identified in non-alcoholic fatty liver di
Updated : 3 years, 2 months ago IST
Researchers have uncovered novel candidate drug targets for non-alcoholic fatty liver disease (NAFLD) by using the latest technologies, including both single-nuclear sequencing of mice and human liver tissue and advanced 3D glass imaging of mice to characterize key scar-producing liver cells
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Study finds excess folic acid during pregnancy effects brain development o
Updated : 3 years, 2 months ago IST
High levels of folic acid during pregnancy were found to harm embryo brain development in pregnant mice. According to the researchers, the findings indicate that more research into the best recommended dosage for pregnant women is required.
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Cellular messengers improve cancer therapy: Research
Updated : 3 years, 2 months ago IST
Nano-sized membrane bubbles known as extracellular vesicles activate the immune system in mice and seem to render their tumours sensitive to a type of immunotherapy drug called a checkpoint inhibitor. This is according to a new study published in Cancer Immunology Research by researchers at
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Unveiling the mysteries of senescent cells and their effect on aging and h
Updated : 3 years, 2 months ago IST
Multiple researchers at the Jackson Laboratory are taking part in an ambitious research program spanning several top research institutions to study senescent cells. Senescent cells stop dividing in response to stressors and seemingly have a role to play in human health and the aging process.
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Researchers use technology to show organoids respond to external sensory s
Updated : 3 years, 2 months ago IST
A team of engineers and neuroscientists has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals' cortex and responded to external sensory stimuli. The implanted organoids reacted to visual stimuli in the same wa
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Research suggests direct connection between spatial goals, behaviour in br
Updated : 3 years, 2 months ago IST
Mice use a specific brain mechanism to automatically flee to cover when threatened, according to study results from the Sainsbury Wellcome Centre and the Gatsby Computational Neuroscience Unit at UCL. Neuroscientists have never before been able to establish such a strong connection between s
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Study finds good-bad feelings for brain stem serotonin
Updated : 3 years, 2 months ago IST
New insights into the opposing actions of serotonin-producing nerve fibres in mice could lead to drugs for treating addictions and major depression.
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Study reveals insights into the opposing actions of serotonin-producing ne
Updated : 3 years, 2 months ago IST
New insights into the opposing actions of serotonin-producing nerve fibres in mice could lead to drugs for treating addictions and major depression.
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Study gives new insight into serotonin-producing nerve fibres in mice
Updated : 3 years, 2 months ago IST
Drugs for the treatment of serious depression and addiction may result from new understandings of the competing effects of serotonin-producing nerve fibres in mice.
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Researchers reveal how ammonia dysregulates T cell function
Updated : 3 years, 2 months ago IST
According to new research, mice with colorectal cancer who have tumours with high levels of ammonia have fewer T cells and are less responsive to immunotherapy. Ammonia, which is crucial for anti-tumor immunity, has been demonstrated to impede the proliferation and operation of T cells.
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Study suggests cancer therapy can be improved by cellular messengers
Updated : 3 years, 2 months ago IST
The findings of a new study suggest that nano-sized membrane bubbles known as extracellular vesicles activate the immune system in mice and seem to render their tumours sensitive to a type of immunotherapy drug called a checkpoint inhibitor.
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