Despite a defeat in the last T20I, Temba Bavuma's side will take chances and will try to once again get back in winning form. While India will look forward to continuing their winning run against Proteas to level the series.
India clinched a win against South Africa in the third T20I to stay alive in the series and the two sides will clash with each other in the penultimate encounter in Rajkot.
Markram spent seven days in quarantine after testing positive for COVID-19 last week and will not be able to complete his return-to-play schedule in time
South Africa are currently playing without their star wicketkeeper-batter Quinton de Kock as he sustained a wrist injury during the first T20I match on June 9 and was forced to miss the second and the third clash.
For Men in Blue, Chahal and Harshal Patel starred with the ball as they bagged three and four wickets respectively to derail the visitors' chase. Bhuvneshwar Kumar and Axar Patel scalped one wicket apiece.
An all-round performance by India helped them in defeating South Africa by 48 runs in the third T20I of five-match series at Dr Y.S. Rajasekhara Reddy ACA-VDCA Cricket Stadium in Visakhapatnam on Tuesday.