India clinched a win against South Africa in the third T20I to stay alive in the series and the two sides will clash with each other in the penultimate encounter in Rajkot.
Markram spent seven days in quarantine after testing positive for COVID-19 last week and will not be able to complete his return-to-play schedule in time
Chasing 149 for the win, Heinrich Klassen took the game away from India with a 46-ball 81 as South Africa romped home with four wickets to spare to go 2-0 up in Cuttack.
An explosive knock from Klaasen (81) powered South Africa to a four-wicket win over India in the second T20I of the five-match series at Barabati Stadium in Cuttack on Sunday.