Gene mutations are the cause of cancer. Tumor suppressors and oncogenes are the two main groups of these altered genes in cancer. Mutations in oncogenes can drive cell proliferation, pushing the gas pedal all the way to the floor, whereas mutations in tumour suppressor genes can cause tumour
Cancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumour suppressors and oncogenes. Mutations in tumour suppressor genes can allow tumours to grow unchecked - a case of no brakes - while mutations in oncogenes can activate cell prolif
Most proteins localize to distinct protein-rich droplets in cells, also known as "cellular condensates". Such proteins contain sequence features that function as address labels, telling the protein which condensate to move into. When the labels get screwed up, proteins may end up in the wron
Around 100 million years ago, a group of land-dwelling turtles took to the oceans, eventually evolving into the sea turtles that we know today. However, the genetic foundations that have enabled them to thrive in oceans throughout the world have remained largely unknown.
New Delhi [India], February 8 (ANI/NewsVoir): Each year in India, more than 200,000 children are born with a defect in their hearts. Out of these approximately 70,000 are critical defects meaning that these children need medical intervention within the first year of their life to survive.
An innovative technique from Cornell University researchers discovered that seminal fluid protein which is transferred from male to female fruit flies during mating changes the expression of genes related to the fly's circadian clock.
An innovative technique from Cornell University researchers finds seminal fluid protein transferred from male to female fruit flies during mating changes the expression of genes related to the fly's circadian clock.
The speed of environmental change is very challenging for wild organisms. When exposed to a new environment individual plants and animals can potentially adjust their biology to better cope with new pressures they are exposed to -- this is known as phenotypic plasticity.
A group of researchers from the Graduate School of Medicine at Nagoya University in Japan have discovered the impact of microRNA (miRNA) on inflammation in lupus in mice. They identified two miRNAs that are downregulated in the disease and an uncommon situation that occurs in which multiple
Bengaluru (Karnataka) [India], January 25 (ANI/PRNewswire): A 34-year-old Suma (name changed), diagnosed with Homozygous Familial Hypercholesterolemia (HoFH) since 2014 was referred to Manipal Hospital, Old Airport Road, Bengaluru. HoFH is a condition where two abnormal genes one from each p
Even though they both develop in the same person and share the same genes, skin cells and brain cells are clearly distinct. They differ because each cell type expresses a unique set of genes that are distinct from those expressed by the other. This is made possible by cellular mechanisms tha