St. Jude Children's Research Hospital scientists have developed an integrated, high-throughput system to better understand and possibly manipulate gene expression for the treatment of disorders such as sickle cell disease and beta thalassemia. The research appears today in the journal Nature
According to a new study, fossils of a tiny sea creature with a delicately preserved nervous system solve a century-old debate over how the brain evolved in arthropods, the most species-rich group in the animal kingdom. Combining detailed anatomical studies of the fossilized nervous syste
According to a new study, fossils of a tiny sea creature with a delicately preserved nervous system solve a century-old debate over how the brain evolved in arthropods, the most species-rich group in the animal kingdom. Combining detailed anatomical studies of the fossilized nervous system w
A form of blood cancer known as mantle cell lymphoma is critically dependent on a protein that coordinates gene expression, such that blocking its activity with an experimental drug dramatically slows the growth of this lymphoma in preclinical tests, according to a study from Weill Cornell M
Washington [US], October 8 (ANI): Our genetics, the environment and our age all play important roles in our health, but which of these is the most important? A new study suggests that in many cases, age plays a more important role than genetics in determining which genes in our bodies are tu
Maryland [US], October 7 (ANI): The arrangement of human retinal cell chromatin, the fibres that wrap 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell's nucleus, was mapped by National Eye Institute researchers. The resultant complet
Washington [US], October 4 (ANI): The bacterium that causes tuberculosis has a cousin you've never heard of: MAC. This bacterial complex is everywhere, but most people never show symptoms. Yet some people get very, very sick. Researchers have now uncovered an immunologic defect that could ex
California [US], October 4 (ANI): Everybody occasionally breathes in Mycobacterium avium complex (MAC) bacteria, yet the majority of individuals don't become ill. These dangerous Mycobacterium tuberculosis cousins usually spend their brief, innocuous lives in food, soil, water, or dust.
Houston [Texas], July 2 (ANI): According to research, DNA methylation in bacteria regulates virulence, reproduction, and gene expression. DNA methylation is crucial for controlling the tissue-specific gene expression that determines a cell's identity, such as whether it is a skin cell or a b
Toronto [Canada], June 29 (ANI): Tadpoles have a good underwater vision, but what happens when they develop into frogs and spend most of their time on land? In quest of the solution, scientists from York University and a number of other institutions discovered that tadpoles' eyes go through
Washington [US], June 26 (ANI): A new study at the University of Alabama suggests that while lower vertebrates can repair their adult hearts after a heart attack, mammals and humans. The ability to regenerate dead muscle tissue in mammalian hearts disappears just a few days after birth becau
Washington [US], June 18 (ANI): Scientists are starting to understand the precise workings of a type of gene that, unlike other genes, does not code for proteins - the building blocks of life.