The human immune system is a very intricate network of cells, signals, and reactions that is strictly regulated in order to ensure that the body can fight off infection without injuring its own tissues
Researchers have developed a brand-new method for locating and eliminating cancer cells by using synthetic DNA. The procedure was successful in lab tests against cells generated from human cervical cancer, human breast cancer, and mouse malignant melanoma.
An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine. The finding suggests that the enzyme may be a potential target for f
Anthracyclines are a class of chemotherapies effective in treating many forms of cancer, including leukemias, lymphomas and breast cancer. Anthracyclines -- such as doxorubicin, frequently used against breast cancer -- kill cancer cells by damaging their DNA.
Researchers have discovered an unknown biological process that controls the production of vital cells that carry oxygen throughout the body. The discovery could help doctors develop new treatments for anaemias that affect millions of people.
Neurodegenerative and psychiatric illnesses can be brought on by inflammation and an overactive immune system in the brain, which results in the loss of synapses and the death of neurons.
A remote fear memory is a memory of traumatic events that occurred in the distant past, a few months to decades ago. A University of California, Riverside, mouse study published in Nature Neuroscience has now spelt out the fundamental mechanisms by which the brain consolidates remote fear me
Scientists used patient stem cells and 3D bioprinting to produce eye tissue that will advance understanding of the mechanisms of blinding diseases. The research team from the National Eye Institute (NEI), part of the National Institutes of Health, printed a combination of cells that form the
The microscopic biological structures known as germinal centres are the immune system's weapons-development facilities if B cells are the immune system's munitions manufacturers, producing antibodies to eliminate hazardous infections.
According to new research, mice with colorectal cancer who have tumours with high levels of ammonia have fewer T cells and are less responsive to immunotherapy. Ammonia, which is crucial for anti-tumor immunity, has been demonstrated to impede the proliferation and operation of T cells.
The immune system, including T cells, is known to be compromised by severe viral infections and cancer, a condition known as immunological 'exhaustion'. The development of novel medicines for cancer or severe viral infections has a major focus on overcoming immunological fatigue.