A syndrome known as immunological "exhaustion" occurs when the immune system, particularly T cells, are severely weakened by cancer and severe viral infections. Overcoming immunological exhaustion is a key goal in the development of new drugs for serious viral infections or cancer.
New research published today by the University of Southampton shows new insight into how our brain develops, which can pave the way for treating neurological disorders.
A research review into molecular insights of a licorice-derived substance called glycyrrhizin for preventing or treating cancer suggests further research could lead to specific agents for clinical use.
A research team at the Cluster of Excellence Physics of Life of TU Dresden and the University of California, Santa Barbara, reveals how cells sense their mechanical environment as they build tissues during embryogenesis.
Recent pressure to maximize vaccine efficacy has stirred up many new discoveries within immunology, revealing numerous paradigms with untapped therapeutic potential.
Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel immunotherapy combination, targeting checkpoints in both T cells and myeloid suppressor cells.
Neutropenia--low levels of white blood cells called neutrophils, which fight infection--develops in more than 80 per cent of patients who receive chemotherapy for blood cancer. It occurs because chemotherapy destroys neutrophils along with tumour cells.
Amyloid beta, a protein known to build up in the brains of Alzheimer's patients, also helps skin cancer cells thrive when they spread to the brain, a new study finds.
Multiple researchers at the Jackson Laboratory are taking part in an ambitious research program spanning several top research institutions to study senescent cells. Senescent cells stop dividing in response to stressors and seemingly have a role to play in human health and the aging process.
Researchers at the University of California, Irvine have discovered a connection between metabolic abnormalities that affect the growth of the brain's oligodendrocyte cells and the mutation that results in Huntington's disease. They discovered that thiamine and biotin in large amounts can re
Scientists from the USC Stem Cell laboratory of Neil Segil have identified a natural barrier to the regeneration of the inner ear's sensory cells, which are lost in hearing and balance disorders. Overcoming this barrier may be a first step in returning inner ear cells to a newborn-like state