Omega 3 fatty acids hold the key stop cancer

Updated:7 years, 3 months ago

New Delhi, Jul 15 (ANI): A study has found that a class of molecules formed when the body metabolises omega-3 fatty acids could inhibit the spreading and growth of cancer. Researchers have found that in mices, the molecules called endocannabinoids, are made naturally by the body and have similar properties to cannabinoids found in marijuana - but without the psychotropic effects. In mice with tumors of osteosarcoma - a bone cancer that is notoriously painful and difficult to treat - endocannabinoids slowed the growth of tumors and blood vessels, inhibited the cancer cells from migrating and caused cancer cell death. The researchers found that in higher concentrations, EDP-EAs did kill cancer cells, but not as effective as other chemotherapeutic drugs on the market. They slowed tumor growth by inhibiting new blood vessels from forming to supply the tumor with nutrients, they prevented interactions between the cells, and most significantly, they appeared to stop cancerous cells from migrating. The researchers isolated the most potent of the molecules and are working to develop derivatives that bind better to the cannabinoid receptor, which is plentiful on the surface on cancer cells. The study appeared in the Journal of Medicinal Chemistry.

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