Immune system discovery paves way to lengthen organ transplant survival: Study

Updated:5 years, 5 months ago

New Delhi, May 10 (ANI): While the chronic rejection of transplanted organs is the leading cause of transplant failure, a new discovery suggests that the innate immune system can specifically remember foreign cells, which could pave the way to drugs that lengthen long-term survival of transplanted organs. The new discovery, led by researchers at the University of Pittsburgh School of Medicine and Houston Methodist Hospital, based on results in a mouse model, were published in the journal Science. The immune system is composed of innate and adaptive branches. The innate immune cells are the first to detect foreign organisms in the body and are required to activate the adaptive immune system. Immunological "memory" -- which allows our bodies to remember foreign invaders so they can fight them off quicker in the future -- was thought to be unique to the adaptive immune system. Vaccines, for example, take advantage of this feature to provide long-term protection against bacteria or viruses. Unfortunately, this very critical function of the immune system is also why transplanted organs are eventually rejected, even in the presence of immune-suppressing drugs. The finding has implications beyond transplantation, according to Oberbarnscheidt. "A broad range of diseases, including cancer and autoimmune conditions, could benefit from this insight. It changes the way we think about the innate immune system."

Top Videos

Updated:4 years, 9 months ago

Pan-India dry run for COVID vaccine tomorrow: Harsh Vardhan

Updated:4 years, 9 months ago

PM Modi joins world leaders in condemning US Capitol siege

Updated:4 years, 10 months ago

Indo-Japan Samvad: Buddha’s message spread out from India to world, says PM Modi

Updated:4 years, 10 months ago

Centre preparing with states for past 4 months for COVID-19 vaccination: Harsh Vardhan

Updated:4 years, 10 months ago

In Jan, India may be in position to give 1st COVID vaccine shot: Harsh Vardhan

Updated:4 years, 10 months ago

Worst is over but still need to be cautious: Health Minister on COVID-19 cases in India

Immune system discovery paves way to lengthen organ transplant survival: Study

Top Videos

Related Video

Aggressive intervention recommended to prevent pediatric diabetes, finds study

Study reveals high fat diets may over-activate destructive heart disease protein

Consuming diet high in poor quality carbohydrates linked to heart attacks, death risk

Researchers find light activities may help women's mobility during ageing

COVID antibodies are transferred from pregnant women to their babies

Overweight, diabetic people at risk of developing nonalcoholic fatty liver disease

Study reveals factors linked with elevated risk of bone fracture

Damage to heart found in more than half of COVID-19 patients discharged from hospital

LGB people more prone to mental health disorders, alcohol misuse

Unacceptably high levels of carcinogens inhaled by commuters

Post-surgery in kids, aspirin preferred to prevent blood clots

Coffee consumption related with decreased heart failure risk

Study reveals high blood pressure causes atrial fibrillation

Greater retail availability of marijuana, alcohol linked with co-use among teens

COVID-19 patients have higher risk of dying after cardiac arrest

World Cancer Day: Understanding role of nutrition, lifestyle changes to control cancer

Pregnancy complications increase risk of heart disease in women

Antibiotic may improve depressive symptoms in people with low-level inflammation: Study

Serious complications during pregnancy linked to higher risk of death: Study

Study reveals what causes irritable bowel syndrome