A molecular mechanism important for the development of pancreatic cancers has been found by researchers at the University of California, San Diego School of Medicine. The mechanism could possibly contribute to the disease's great resistance to treatment and proclivity for metastasis.
A new atlas maps more than 300 protein kinases found in human cells and identifies which types of protein substrates they target. The atlas could help scientists understand what happens when cells become cancerous or are treated with specific drugs.
Researchers have uncovered a series of molecular interactions that may be crucial in preventing the spread of cancer cells. There is currently no effective therapeutic strategy to stop metastasis, which is the main cause of death from solid malignant tumours.
Hepatocellular carcinoma (HCC), the most common type of liver cancer, is already the third leading cause of cancer-related deaths worldwide--and cases are on the rise in both the United States and around the world. While chemotherapy, surgery, and liver transplants can benefit some patients,
Barrett oesophagus is a genetic mutation in the esophageal mucous membrane that can lead to esophageal cancer. If certain biomarkers, known as miDNA, which are extremely short DNA strands, are found in these tissue alterations, it could be an indication that this preliminary stage of esophag
Mumbai (Maharashtra) [India], January 3 (ANI/PRNewswire): Datar Cancer Genetics announced today that the US Food and Drug Administration (FDA) has granted 'Breakthrough Device Designation' for its 'TriNetra™-Glio', a blood test to help in the diagnosis of brain tumors. This is the thir
Mount Sinai researchers have made two important discoveries about the mechanism by which bladder cancer cells foil attacks from the immune system. The research, published in Cancer Cell in September, could lead to a new therapeutic option for patients with these types of tumors.
Inflammatory bowel disease (IBD) is an umbrella term for two diseases, Crohn's disease and ulcerative colitis, that are characterized by the prolonged inflammation of the gastrointestinal tract. This condition often leads to the development of colorectal tumors. Understanding the pathogenesi
According to new research, mice with colorectal cancer who have tumours with high levels of ammonia have fewer T cells and are less responsive to immunotherapy. Ammonia, which is crucial for anti-tumor immunity, has been demonstrated to impede the proliferation and operation of T cells.
After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain tumors, blood cancers and Kleefstra syndrome a rare genetic, neurocog
The surgical approach is frequently not decided when a patient has surgery to remove a tumour or treat an illness. In order to decide how much tissue needs to be removed, surgeons need to know more about the condition they are treating, such as a tumor's margins, its stage, and whether a les