A new study provided a deeper understanding of the vast diversity of T cell states, as well as their relationships and roles within the complex tumour microenvironment, bringing a new perspective to understanding immunotherapy efficacy in cancer.
Isolated from other cells in a laboratory dish, tumour cells won't reveal their actual nature. Rice University researchers created an improved tumour model that houses osteosarcoma cells alongside immune cells known as macrophages inside a three-dimensional framework designed to simulate bon
The source of tumour cell resistance to immunotherapy was identified by a recent study that examined the pancreatic cancer tumour microenvironment, and novel therapeutic approaches were developed as a result.