A novel brain link may provide a new therapeutic target for the treatment of mental illness by explaining how early stress and adversity cause the reward circuit in the brain to function improperly. This circuit's dysfunction is regarded to be the root cause of a number of severe illnesses,
The researchers created new human organoid models of fatty liver disease. They used these models to shed light on drug responses and built a CRISPR-screening platform to find new disease mediators and potential therapeutic targets. These models will aid in the testing and development of nove
Inflammatory bowel disease (IBD) is an umbrella term for two diseases, Crohn's disease and ulcerative colitis, that are characterized by the prolonged inflammation of the gastrointestinal tract. This condition often leads to the development of colorectal tumors. Understanding the pathogenesi
Researchers have now discovered that a receptor involved in our sensation of touch and warmth is present in our colon, opening up a potential therapeutic target for the management of chronic pain brought on by gastrointestinal conditions like irritable bowel syndrome.
Cancer cells require proteins that bind copper ions in order to develop and spread throughout the human body. Recent studies on the interactions between proteins and how they bind to metals in cancer-related proteins have revealed possible new therapeutic targets.
Specialized channel proteins are possible therapeutic targets for sleep apnea and similar abnormally slow breathing disorders in obese people, suggest Johns Hopkins Medicine researchers who did a study on mice.
Specialized channel proteins are possible therapeutic targets for sleep apnea and similar abnormally slow breathing disorders in obese people, suggest Johns Hopkins Medicine researchers who did a study on mice.
Washington [US], September 26 (ANI): New ways to study why an antibiotic causes hair cell death and permanent hearing loss in people are being developed by researchers at Indiana University School of Medicine.
Washington [US], September 2 (ANI): Scientists hypothesize that circadian rhythm disruption is a psychopathology factor shared by a broad range of mental illnesses and that research into its molecular foundation could be key to unlocking better therapies and treatments.
Washington [US], August 4 (ANI): Researchers have discovered a therapeutic target for the preservation and regeneration of beta cells ( cells), the cells in the pancreas that produce and distribute insulin. This finding could be a game-changer for patients with type 2 diabetes. The discovery
Geneva [Switzerland], March 19 (ANI): Scientists from the University of Geneva have identified a key protein in flies, and also in mice, which plays a protective role against Parkinson's disease and could be a new therapeutic target.