Loss of synapses and the death of neurons, leading to neurodegenerative and psychiatric diseases can be caused by inflammation and overactivation of the immune system in the brain.
Neuromuscular disorders affect millions of people worldwide. Now a discovery made at the Montreal Clinical Research Institute of Montreal (IRCM) opens the door to the development of targeted therapies.
The outer layer of skin, the epidermis, is constantly turning over to replace dead or damaged cells throughout our lifetime. Skin stem cells need to continuously make decisions: either make more copies of themselves (self-renewal) or switch their fate towards differentiation. The molecular m
New research has uncovered how genetic changes that accumulate slowly in blood stem cells throughout life are likely to be responsible for the dramatic change in blood production after the age of 70.
A team coaxed stem cells to take on the characteristics and functions of a human adrenal gland, progress that could lead to new therapies for adrenal insufficiencies and a deeper understanding of the genetics of such disorders.
Researchers generated induced pluripotent stem cells (iPSCs) and cerebral organoids from the last male Malaysian Sumatran rhino, according to a study published in the journal iScience on October 20. As noted by the authors, the organoids could contribute to knowledge about the evolutionary p
Bengaluru (Karnataka) [India], November 8 (ANI/NewsVoir): Prapul (21) and Prajwal (24), siblings from Bengaluru helped save the lives of two blood cancer patients.
New York [US], September 22 (ANI): According to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian, the New York Genome Center, Harvard Medical School, and Dana-Farber Cancer Institute, a typical, spontaneous mutation in blood stem cells, which has been linked to h
Washington [US], September 14 (ANI): Biomedical engineers and medical researchers at UNSW Sydney have independently made discoveries about embryonic blood stem cell creation that could one day eliminate the need for blood stem cell donors.
Washington [US], September 8 (ANI): A new study reveals how mechanical forces and tissue mechanics influence the morphology of the developing brain, and establishes a direct link in neural stem cells between Piezo1, a mechanically-activated ion channel, and intracellular cholesterol levels d
Washington [US], September 2 (ANI): Mitochondria are fascinating shape-shifting organelles that have long been recognized as the powerhouses of our cells. However, little is known about how the continuous fission and fusion of these small energy sources affect stem cell activity and tissue r
Washington [US], September 2 (ANI): Scientists have managed to generate a new type of human cell in the lab using stem cells. The new cells closely resemble their natural counterparts in early human embryos. As a result, researchers can now better study what happens just after an embryo impl