Previous studies identified the proteins Atg15, Pep4, and Prb1 as essential actors in this process. However, the relationship between these proteins and the underlying mechanisms remains unknown. A research team has recently made significant progress towards solving this puzzle.
A Duke Health team has discovered a way to launch a molecular warhead that can eradicate the bacterium that causes Lyme disease, using a method that has demonstrated promise in targeting cancer tumours.
Researchers discovered that when the connection isn't made correctly, the behaviour might suffer. In mice, for example, disruptions to the proteins' capacity to interact led to increased hyperactivity, decreased risk avoidance, and memory impairments.
Scientists at The University of Toledo have shown that engineered bacteria can lower blood pressure and the finding opens avenues to harness the body's own microbiome to treat hypertension
Mumbai (Maharashtra) [India], October 14: The Good Food Institute India (GFI India), the central expert organization, thought leader, and convening body in the alternative protein sector marks the conclusion of the 3rd edition of its flagship program, The India Smart Protein Innovation Chall
In theory, a team from the University of Massachusetts Amherst proved that a protein antigen from a childhood vaccine may be administered into the cells of a malignant tumour to reorient the body's immune system against the cancer, effectively stopping it and preventing its recurrence.
Once assumed to be the cell's trash can, a little bubble of biological debris, termed the midbody remnant, is packing working genetic material with the ability to affect the fate of other cells, even turning them into cancer
The collection of chemicals known as amyloid peptides is thought to be an early driver of Alzheimer's disease. These trigger cell death and are typically found in Alzheimer's patients' brains. Researchers at Chalmers University of Technology in Sweden have now demonstrated that after being t
When the UPS mechanism fails, cells engage in a compensatory protein clearance process known as "aggrephagy," in which protein aggregates are destroyed in a controlled manner by the cell.
The human lymphatic system is a huge network of tubes that drain and transfer protein-rich fluid from tissues to lymph nodes. When the machinery malfunctions and the lymphatic vessels fail to drain properly, fluid builds up in the tissues, causing painful swelling known as lymphedema.
When damaged liver cells are replaced by scar tissue, hepatic fibrosis results. Cirrhosis, liver failure, and even liver cancer can arise as a result of cumulative scarring that, over time, restricts the blood flow to the liver. When the condition is severe, there is no other course of actio
Under normal conditions, tau protein is a vital component of the brain's infrastructure, helping to stabilise neurons into their appropriate forms. However, tau can become tangled and toxic, harming brain tissue and generating tauopathies, a category of brain illnesses characterised by diffi