New research has revealed how the tau protein, a critical element in the formation of Alzheimer's disease, is also involved in normal learning processes in the healthy brain, potentially providing a focal point for future drug therapies.
Hepatocellular carcinoma (HCC), the most common type of liver cancer, is already the third leading cause of cancer-related deaths worldwide--and cases are on the rise in both the United States and around the world. While chemotherapy, surgery, and liver transplants can benefit some patients,
Published today in Stem Cell Reports, researchers from the University of Minnesota Medical School discovered two signaling pathways that are downregulated in human hearts after birth. These pathways, mitogen-activated protein kinase (MAPK) and phosphoinositide 3-kinase (PI3K)-AKT, lead to ma
Scientists have demonstrated how time-restricted eating influences gene expression in more than 22 different areas of the body and brain. Gene expression is the process by which genes are activated and respond to their surroundings by producing proteins.
Research from the University of Virginia School of Medicine suggests how a newly developed gene therapy can treat Dravet syndrome, a severe form of epilepsy, and potentially prolong survival for people with the condition.
A new method can illuminate the identities and activities of cells throughout an organ or a tumour at unprecedented resolution, according to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center.
As cells perform their everyday functions, they turn on a variety of genes and cellular pathways. MIT engineers have now coaxed cells to inscribe the history of these events in a long protein chain that can be imaged using a light microscope.
The method, described in the study published journal 'Nature Biotechnology,' records gene activity patterns and the presence of key proteins in cells across tissue samples while retaining information about the cells' precise location. This allows for the creation of complex, data-rich "maps"
Plants are frequently grown for research purposes under stable lighting, which does not mimic natural conditions. Researchers revealed the importance of two key proteins for the dynamic control of photosynthesis in a series of experiments with changing light conditions, simulating the natur
X-rays cause damage to living tissue, there are clear medical reasons to limit your exposure to radiation. Researchers use increasingly powerful X-ray sources in basic research on the properties and characteristics of mineralised tissue samples such as bone.