Iron (Fe) accumulates in the brain cortex with aging. A plethora of studies indicate that progressive iron accumulation in the substantia nigra (SN) in the aged human brain is a major risk factor for Parkinson's disease (PD) and other neurodegenerative diseases, but not everyone. This is bec
Wasteosomes, structures that act as storage facilities for waste products from the brain, are used to demonstrate the malfunction of the glymphatic system, a recently identified system that is a crucial brain-cleaning mechanism.
A team of researchers led by Swansea University have developed new technology to monitor cholesterol in brain tissue which could uncover its relation to neurodegenerative disease and pave the way for the development of new treatments.
Dementia encompasses a range of neurodegenerative conditions that lead to memory loss and cognitive deficiencies and affect some 55 million people worldwide. Yet despite its prevalence, there are few effective treatments, in part because scientists still don't understand how exactly dementia
Singapore, October 19 (ANI): Researchers discovered that turning on stress response in cells at a post-reproductive age could be the key to slowing ageing and promoting longevity.
New York [US], September 21 (ANI): According to a new study led by Weill Cornell Medicine researchers, aggregates of the protein alpha-synuclein spread in the brains of people with Parkinson's disease via a cellular waste-ejection process.
Washington [US], September 16 (ANI): Infections treated with speciality hospital care in early and mid-life are associated with an increased subsequent risk of Alzheimer's (AD) and Parkinson's diseases (PD), but not amyotrophic lateral sclerosis (ALS), according to a new study.
Washington [US], September 11 (ANI): Researchers at the National Center for Advancing Translational Sciences (NCATS), Mount Sinai's Icahn School of Medicine, and other organisations have successfully reversed the effects of several lethal inherited neurodegenerative diseases known as lysosom
Washington [US], September 9 (ANI): Scientists at Mount Sinai's Icahn School of Medicine, the National Center for Advancing Translational Sciences (NCATS), and other institutions have reversed the effects of several life-threatening inherited neurodegenerative diseases known as lysosomal st
Washington [U.S], July 21 (ANI): Neurodegenerative diseases like Alzheimer's disease or Parkinson's disease are caused by folding errors (misfolding) in proteins or peptides, i.e. by changes in their spatial structure. This is the result of minute deviations in the chemical composition of th
Washington [US], July 9 (ANI): Copper exposure in the environment and the protein alpha-synuclein in the human brain could play an important role in the pathogenesis of Parkinson's disease. Researchers were able to show how the protein takes on an unusual shape when exposed to large amounts