Almost 35 million adults in the U.S. suffer from osteoarthritis, a degenerative joint condition caused on by cartilage breakdown. Although the precise cause of cartilage destruction in osteoarthritis is uncertain, mechanical stress damage with insufficient self-repair is thought to be the ma
Scientists at UC San Francisco (UCSF) have created the first molecular-level, 3D picture of how an odour molecule activates a human odorant receptor, breaking a long-standing impasse in our understanding of olfaction.
A concern to global health is antibiotic resistance. Antibiotic-resistant bacterial infections were blamed for an estimated 1.3 million deaths globally in 2019 alone. Researchers at Baylor College of Medicine have been examining the mechanism that fuels antibiotic resistance at the molecular
"The samples will be collected from selected state-run hospitals, tested in the InDNA laboratory at Bhubaneswar, and reports would be submitted back to the Institutions," Odisha government said in a statement.
Many vaccines contain compounds known as adjuvants in addition to an antigen that stimulates the immune system. A Chinese research team has now created two novel broad-spectrum adjuvants that can dramatically boost the immune response to vaccines using computer-aided molecular design and ma
The study has described --in patients and animal model samples of type 2 diabetes-- a decrease in mitochondrial proteins that synthesize complex subunits of the respiratory chain. This decrease in proteins is associated with an increase in intracellular nitric oxide which, according to the r
In Molecular Metabolism, a Rutgers study found that early overnutrition rewires developing brains to seek unhealthy food in children whose mothers are overweight during pregnancy and nursing.
Researchers at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences characterize how the enzyme PCYT2 affects muscle health in disease and aging in laboratory mouse models. The findings are published on in Nature Metabolism.
According to a Rutgers study published in Molecular Metabolism, people whose moms are overweight during pregnancy and nursing might become obese as adults because early overnutrition rewires developing brains to crave unhealthy food
Personalization of cancer treatments has long been a goal--finding the right drugs that work for a patient's specific tumour based on specific genetic and molecular patterns. Many of these targeted therapies are highly effective, but they are not available for all cancers, including NSCLCs w
When these POMC neurons become super active, these sort of behavioural problems result and when scientists reduce their activity, it reduces the behaviours. The report was published in the journal Molecular Psychiatry.