Search For "interferon"
Autoantibodies can be behind lifelong risk of viral infections: Study
Updated : 5 months, 1 week ago IST
A new study shows that about two per cent of the population develop autoantibodies against type 1 interferons, mostly later in life. This makes individuals more susceptible to viral diseases like COVID-19. The study, conducted by University of Zurich (UZH) researchers together with a USZ tea
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Researchers give more insight into development of lupus in females
Updated : 2 years, 4 months ago IST
For many years, healthcare professionals have known that lupus, an autoimmune disease, affects women nine times more than males. Some of the variables that contribute to the disease's high incidence in women have remained unknown, but Johns Hopkins Medicine researchers have found answers in
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Researchers reveal role of polyphenols in regulating inflammatory immune r
Updated : 3 years ago IST
PCB2DG, an anti-inflammatory polyphenol, inhibits glutamine absorption by targeting and directly interacting with the main glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2). This reduction in intracellular glutamine accumulation in CD4+ T cells also inhibits the pr
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Study reveals how gene signaling rewires tumors after immunotherapy
Updated : 3 years, 1 month ago IST
A mechanism has been identified by researchers from the University of Michigan Rogel Cancer Center that explains why some patients' cancers grow in response to immunotherapy rather than shrinking.
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Anifrolumab has shown long-term efficiency in lupus patients: Study
Updated : 3 years, 4 months ago IST
Type I interferon (IFN) is a strong immune activator found in high concentrations in the majority of patients with lupus, an autoimmune disease. In Arthritis & Rheumatology, researchers report positive results from the first placebo-controlled long-term trial of anifrolumab, a human mon
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Study finds how innate immune system fights infectious agents
Updated : 3 years, 4 months ago IST
Researchers revealed how innate immune system fights infectious agents and why the alarm messenger type I interferon is important for this process.
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DGCI approves emergency use of Zydus's Virafin in treating moderate COVID-
Updated : 4 years, 10 months ago IST
New Delhi [India], April 23 (ANI): Zydus Cadila received emergency use approval from the Drugs Controller General of India (DGCI) on Friday for the use of 'Virafin', Pegylated Interferon alpha-2b (PegIFN) in treating moderate COVID-19 infection in adults.
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Zydus' Virafin gets emergency use approval for treating moderate COVID-19
Updated : 4 years, 10 months ago IST
New Delhi [India], April 23 (ANI): The Drugs Controller General of India (DGCI) has approved emergency use for Zydus Cadila's Pegylated Interferon alpha-2b, 'Virafin' for treating moderate COVID-19 infection in adults.
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Four drugs for COVID-19 appear to have little or no effect on reducing mor
Updated : 5 years, 4 months ago IST
New Delhi [India], October 17 (ANI): The interim analysis of WHO's Solidarity Trial has revealed that 4 repurposed drugs for COVID-19--remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon regimens-- appeared to have little or no effect on reducing mortality, initiation of venti
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Four repurposed drugs have no effect on reducing mortality in COVID-19 cas
Updated : 5 years, 4 months ago IST
New Delhi [India], October 16 (ANI): The interim analysis of World Health Organisation (WHO)'s Solidarity Trial has revealed that four repurposed drugs for COVID-19--remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon regimens appeared to have little or no effect on reducing m
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Zydus gets Mexican regulator nod to conduct clinical trials with Pegylated
Updated : 5 years, 8 months ago IST
Ahmedabad (Gujarat) [India], July 17 (ANI): Pharmaceutical major Zydus said on Friday it has got approval from Mexico's Federal Commission for the Protection against Sanitary Risk (COFEPRIS) to conduct clinical trials with its biological therapy 'Pegylated Interferon alpha-2b' for the treatm
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Zydus Cadila approaches DCGI to use hepatitis drug for COVID-19 clinical t
Updated : 5 years, 10 months ago IST
New Delhi [India], May 5 (ANI): The country's top drug regulator, Drug Controller General of India (DCGI), has received an application from Zydus Cadila, the leading global pharmaceutical company in India, to conduct clinical trial using antiviral drug 'Pegylated Interferon Alpha-2b' in adul
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