Why do cells, and by extension humans, age? The answer may have a lot to do with mitochondria, the organelles that supply cells with energy. Though that idea is not new, direct evidence in human cells had been lacking.
A recent study finds that severe inflammation reduces the body's ability to eliminate malignant blood cells in persons with acute myeloid leukaemia (AML).
Crohn's disease and the more severe ulcerative colitis cause inflammation of the tissues in the digestive tract. Symptoms can include abdominal pain, severe diarrhoea, fatigue, weight loss, malnutrition, loss of appetite and bloody stools. It is characterized by periods of relaxation and fla
Researchers discovered that an inflammatory trigger similar to that found in viral infections is higher in Alzheimer's disease and progressive supranuclear palsy, a rare brain illness.
Lipopolysaccharide, a virulence factor produced by bacteria, is a toxin that can cause systemic inflammation via circulation. In a recently completed study, genetic markers were discovered that are associated with a heightened lipopolysaccharide level in the blood.
From the complexity of neural networks to basic biological functions and structures, the human brain only reluctantly reveals its secrets. Advances in neuro-imaging and molecular biology have only recently enabled scientists to study the living brain at a level of detail not previously achie
A team led by Van Andel Institute scientists identified two distinct types of obesity, each with physiological and molecular differences that might have long-term implications for health, disease, and medication response.
Inflammatory bowel disease (IBD) is an umbrella term for two diseases, Crohn's disease and ulcerative colitis, that are characterized by the prolonged inflammation of the gastrointestinal tract. This condition often leads to the development of colorectal tumors. Understanding the pathogenesi
Neurodegenerative and psychiatric illnesses can be brought on by inflammation and an overactive immune system in the brain, which results in the loss of synapses and the death of neurons.
A team led by Van Andel Institute scientists has identified two distinct types of obesity with physiological and molecular differences that may have lifelong consequences for health, disease and response to medication.
A recent study from Penn State and the University of Cincinnati suggests that physical problems like inflammation may play a role in the decreased milk production of breastfeeding women, which is one of the main reasons mothers stop breastfeeding early.
Scientists at the Roger Williams Institute of Hepatology, affiliated with King's College London and the University of Lausanne, discovered in a study examining the link between non-alcoholic fatty liver disease (NAFLD) and brain dysfunction that an accumulation of fat in the liver causes a d