From the onset of the disease through the point of androgen independence, where the tumour no longer responds to hormone restriction therapy, researchers have described prostate cancer cell dynamics at a single-cell resolution over the course of the disease.
Graphene oxide, a nanomaterial utilised in everything from electronics to biomolecule sensors, may have an indirect impact on the immune system through the gut microbiome.
A study supports the idea that some T cells that react to microbes also may react to normal human proteins, causing autoimmune disease. The findings promise to accelerate efforts to improve diagnostic tools and treatments for autoimmune diseases.
Karolinska Institutet researchers have demonstrated that B lymphocytes, on which the efficient operation of the immune system depends, can occasionally cause more harm than good since their numbers sharply increase following intestinal trauma, impeding the healing process.
B cells are critical to the proper functioning of the immune system. However, researchers at Karolinska Institutet have shown that they can sometimes do more harm than good, as their numbers greatly increase after bowel damage, preventing the tissue from healing. The results, which are prese
Study found out how immune cells prevent Alzheimer's disease and other forms of cognitive decline. Researchers revealed that boosting these cells could restore the damage.
Scientists at Duke-NUS Medical School and colleagues in Singapore have sequenced the response to viral infection in colony-bred cave nectar bats (Eonycteris spelaea) at single-cell resolution. Published in the journal Immunity, the findings contribute to insights into bat immunity that could
It is possible to determine how quickly the disease might advance by detecting immune cells in the cerebrospinal fluid after diagnosing ALS, according to researchers.
Engineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can do to fight blood cancers. Now, investigators have reported highly promising early results for CAR T therapy in a small set of patients with the autoimmune disease lupus. Penn Medicine C
A form of blood cancer known as mantle cell lymphoma is critically dependent on a protein that coordinates gene expression, such that blocking its activity with an experimental drug dramatically slows the growth of this lymphoma in preclinical tests, according to a study from Weill Cornell M
The study found protein is crucial in helping malignancies avoid immune attacks. The "fragile X mental retardation protein" (FMRP) is a protein that controls a network of genes and cells in the tumor microenvironment that help the tumor "hidden" from immune cells.