Experiments on mice and human cells reveal that the number of specialised immune cells ready to combat skin cancer increased when a novel therapy prevented their egress from melanoma tumours.
Researching the wall separating the circulatory system from the neurological system has been highly difficult or limited in its use of models. In order to properly investigate potential new treatments for brain tumours, researchers have created a more realistic model.
Researchers have uncovered a gene that is overexpressed in mutated IDH1. Studies in human cells and a novel mouse model both show that this gene, called ZMYND8, plays a critical role in radiation resistance. When they knocked down the gene, the glioma cells became responsive to radiation tre
There may be greater public health risks associated with the ultraviolet nail polish drying equipment used to cure gel manicures than previously realised. These ultraviolet (UV) light-emitting devices were studied by researchers at the University of California, San Diego, who discovered that
Why do cells, and by extension humans, age? The answer may have a lot to do with mitochondria, the organelles that supply cells with energy. Though that idea is not new, direct evidence in human cells had been lacking.
Why do cells, and thus people, age? The solution could be related to mitochondria, the organelles that provide energy to cells. Though this is not a new thing, direct evidence in human cells had previously been lacking, until now.
A new atlas maps more than 300 protein kinases found in human cells and identifies which types of protein substrates they target. The atlas could help scientists understand what happens when cells become cancerous or are treated with specific drugs.
Northwestern University-led researchers have created the first highly mature neurons from human induced pluripotent stem cells (iPSCs), a feat that opens new opportunities for medical research and potential transplantation therapies for neurodegenerative diseases and traumatic injuries.
A potentially game-changing treatment for people with, or at risk of, blood clots have been found effective by an international team of researchers led by McMaster University's Jeffrey Weitz.
An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine. The finding suggests that the enzyme may be a potential target for f