Cancer spreads in devious, almost military ways across the human body. It may, for example, alter our genetic make-up, take over certain cell-to-cell signalling mechanisms, and change essential enzymes to enhance tumour development, resistance to medicines, and expedite spread from the initi
Many of the medications we use to treat cancer and infectious disease are - or are derived from natural chemicals, but it's difficult to know how nature assembles them.
According to new research from Ghent, Belgium, intravenous treatment with MK-3402, a metallo-beta-lactamase inhibitor, can be a successful technique in combating antimicrobial resistance. The findings will be presented at ASM Microbe 2023, the American Society for Microbiology's annual meeti
Cisplatin is commonly used as a chemotherapeutic drug in the treatment of many solid tumours, including bladder, ovarian, and esophageal tumours. However, when it is metabolised by an enzyme called "cysteine conjugate beta-lyase 1 (CCBL1)," it is transformed to "thiol-cisplatin," a highly ac
Scientists found that the MGAT5 glycosylation enzyme plays a significant role in brain development. This finding may lead to new therapeutic applications for neural stem cells.
A DNA enzyme, or DNAzyme, has been created by researchers at the University of California, Irvine that can identify between two RNA strands inside a cell and cut the one linked to the sickness while leaving the healthy strand unharmed. This ground-breaking "gene silencing" method may fundame
According to new research, neurodegeneration in brain cells may occur when the normal cellular cleansing mechanism failed owing to declining levels of a coenzyme related to niacin and deprives cells of energy.
Children with recurrent brain tumours tolerated the first in-human trial of a novel immunotherapy well, and many were able to experience unexpected months of a more normal life, according to researchers. Immunotherapy disables a natural enzyme that tumours hijack for their defence.
New research sheds light on how an enzyme that aids in the regulation of ageing and other metabolic processes accesses our genetic material to modify gene expression within the cell.
Researchers at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences characterize how the enzyme PCYT2 affects muscle health in disease and aging in laboratory mouse models. The findings are published on in Nature Metabolism.