For the first time, researchers have identified a distinct molecular mechanism underlying the early phases of programmed cell death, or apoptosis, a process that plays an important role in cancer prevention.
Apoptosis is essential for human life, and its disruption can cause cancerous cells to grow and not respond to cancer treatment. In healthy cells, it is regulated by two proteins with opposing roles known as Bax and Bcl-2.
The study was published in 'Science Advances'.
Two new investigations carried out by global scientists combine genome sequencing of over 800 individuals from 233 primate species, covering nearly half of all existing primate species on Earth, with the study of fossil remains and multiplying by four-fold the number of primate genomes avail
According to a recent study from the University of Pittsburgh, in a mouse model of inflammatory bowel disease (IBD), extra sugar inhibits cells that regenerate the colon's lining. The results, which were published in Cellular and Molecular Gastroenterology and Hepatology, may help to explain
Lead author Carolyn Elya, a postdoctoral researcher in the Department of Organismic and Evolutionary Biology at Harvard, describes the molecular and cellular mechanisms underlying the ability of the parasitic fungus Entomophthora muscae (E. muscae) to influence the behaviour of fruit flies i
Lung disease and air pollution have long been associated with one another. A recent study has identified one biological mechanism that may be responsible for that connection; this finding may offer fresh information on how to cure or prevent diseases caused by exposure to pollution.
To control their activity according to the time of day, organisms rely on a biological clock known as the 'circadian' clock. A central clock, made up of a collection of brain cells known as suprachiasmatic nuclei (SCN), synchronises the circadian clocks found in all of the body's organs, kno
In a cryo-ET experiment, scientists utilise a transmission electron microscope to create 3D images of the cellular volume containing complicated biomolecules, known as tomograms. To obtain a more detailed image of each protein.
Cedars-Sinai Cancer Centre researchers discovered that fatty liver, a condition commonly associated with obesity, promotes the progression of colon cancer to the liver. Their research, which was published in the peer-reviewed journal Cell Metabolism, delves into the process at the cellular l
According to new research, neurodegeneration in brain cells may occur when the normal cellular cleansing mechanism failed owing to declining levels of a coenzyme related to niacin and deprives cells of energy.
Ribonucleic acids (RNAs), single-stranded molecules, are essential parts of every living thing's cells. By carrying the instructions for the synthesis of a protein in their own sequence, mRNAs, which function as "transcripts" of our genes, contribute to the translation of genetic information
Single-stranded molecules called ribonucleic acids (RNAs) are crucial components of every living thing's cells. As "transcripts" of our genes, mRNAs, for instance, play a role in the translation of genetic information by carrying the instructions for the production of a protein in their own