An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine. The finding suggests that the enzyme may be a potential target for f
Anthracyclines are a class of chemotherapies effective in treating many forms of cancer, including leukemias, lymphomas and breast cancer. Anthracyclines -- such as doxorubicin, frequently used against breast cancer -- kill cancer cells by damaging their DNA.
Researchers at UConn Health, Yale, and Johns Hopkins have identified that some cancer cells can "cheat" by escaping constraints imposed by lack of oxygen, allowing the cancer cells to continue to grow.
Surgery requires a variety of instruments and methods, as well as the skill of the surgeon, especially when removing cancerous tumours. Surgery to remove lung cancer tumours will now be a little bit more precise thanks to the new imaging agent Cytalux.
Researchers from UConn Health, Yale, and Johns Hopkins discovered that some cancer cells can "cheat" by evading the limits imposed by a lack of oxygen, allowing the cancer cells to grow.
A novel mechanism that allows cancer cells to spread throughout the body has been discovered by an international team of researchers, offering a potential new target to halt metastasis, which is to blame for 90 per cent of cancer deaths.
In many cancer types, cancer cells try to survive by escaping attack from the immune system. These cancer cells hijack mechanisms called immune checkpoints to trick the immune system into thinking they are healthy cells. Recent advances in cancer treatment have focused on developing immune c
Researchers found and developed nanoparticles that simultaneously carry chemotherapy and a new immunotherapy. Chemotherapy is a pillar of cancer treatment, but residual cancer cells can persist and cause tumor relapse.
Engineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can do to fight blood cancers. Now, investigators have reported highly promising early results for CAR T therapy in a small set of patients with the autoimmune disease lupus. Penn Medicine C
A protein that can predict whether or not DNA-damaging treatments will be effective when it is found in high concentrations in breast cancer tumors, according to researchers.