A novel apparatus that resembles a human vein might be useful for blood clot research and could replace the use of animals in some tests. Researchers at the University of Birmingham have created the vein-on-a-chip model, which may be applied in studies to better comprehend the mechanics unde
The drug, known as AF-130, was tested in an animal model at Waipapa Taumata Rau, the University of Auckland where researchers found it improved the heart's ability to pump, but, equally important, prevented sleep apnoea, which itself reduces lifespan (see Nature Communications).
The study has described --in patients and animal model samples of type 2 diabetes-- a decrease in mitochondrial proteins that synthesize complex subunits of the respiratory chain. This decrease in proteins is associated with an increase in intracellular nitric oxide which, according to the r
A study discovered that changes in the gut microbiota are associated with an increase in oxygen levels in the intestine after immune-mediated intestinal injury. Reducing intestinal oxygen levels pharmacologically eased the microbial imbalance and reduced the severity of intestinal illness.
Researchers found that alterations in the gut microbiome that are linked to graft-versus-host disease severity are connected to an increase in oxygen levels in the intestine
A recent study linked colon cancer risk and exposure to salmonella bacteria. Salmonella infection was connected to colon cancers that started earlier and expanded larger, according to the researchers.
Lacticaseibacillus rhamnosus HA-114, a probiotic bacterium, protects neurons in the C. elegans worm, an animal model used to study amyotrophic lateral sclerosis (ALS).
Long-term use of the food dye Allura Red may increase the incidence of IBDs, Crohn's disease, and ulcerative colitis, according to Waliul Khan of McMaster University. Research using experimental animal models of IBD has shown that prolonged exposure to Allura Red AC is detrimental to intesti
A probiotic bacterium called Lacticaseibacillus rhamnosus HA-114 prevents neurodegeneration in the C. elegans worm, an animal model used to study amyotrophic lateral sclerosis (ALS).
Long-term consumption of Allura Red food dye can be a potential trigger of inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis, says McMaster University's Waliul Khan. Researchers using experimental animal models of IBD found that continual exposure to Allura Red AC ha
In animal models, researchers revealed how water enriched with hydrogen molecules (H2) reduces the symptoms of neuropathic pain and its associated emotional disorders.