Arthur Fils with a fine performance reached his third quarterfinal of the season following a 6-3, 6-3 victory over Thiago Seyboth Wild at the Chile Open in Santiago.
Rublev overcame a significant scare to defeat the Brazilian 7-5, 6-4, 3-6, 4-6, 7-6(10-6) and advance to the second round in Melbourne for the eighth time in eight outings.
Argentine Diego Schwartzman rallied from one set down to upset World No. 8 Taylor Fritz 6-4, 3-6, 7-6(5) and claimed a spot in the Round of 16 at the Shanghai Masters on Monday
Both players competed in 34-degree heat and struggled in humid conditions. Medvedev received two medical timeouts due to high temperature. The rallies between both players were long and lung-busting, but the 27-year-old Medvedev beat Rublev in two hours and 48 minutes.