Search For "amyloid"
Research finds fat may secretly fuel Alzheimer's
Updated : 5 months, 1 week ago IST
Scientists discovered that tiny messengers released by fat tissue, called extracellular vesicles, can carry harmful signals that accelerate the buildup of amyloid-b plaques in the brain.
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Scientists find over 200 hidden proteins that may drive Alzheimer's: Study
Updated : 5 months, 1 week ago IST
A surprising new study has uncovered over 200 misfolded proteins in the brains of aging rats with cognitive decline, beyond the infamous amyloid and tau plaques long blamed for Alzheimer's.
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A new hope for patients suffering from potentially fatal rare heart diseas
Updated : 10 months ago IST
Singapore, May 14: While receiving treatment for a car accident ten years ago, Mr Chua learnt that he had an abnormal build-up of protein in his heart vessels. This discovery led to the diagnosis of a condition known as transthyretin amyloid cardiomyopathy (ATTR-CM), a rare disease currently
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Anti-amyloid drug displays signs of preventing Alzheimer's dementia: Study
Updated : 5 months, 1 week ago IST
The findings suggest -- for the first time in a clinical trial -- that early treatment to remove amyloid plaques from the brain many years before symptoms arise can delay the onset of Alzheimer's dementia
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How brain trauma triggers Alzheimer's disease: Study
Updated : 5 months, 1 week ago IST
A study reveals that traumatic brain injury alters the small vessels in the brain, resulting in an accumulation of amyloid beta -- a hallmark of Alzheimer's disease. The findings suggest that vascular dysfunction could be an early driver in neurodegenerative disorders rather than being caus
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Protein present in brain associated with frontotemporal dementia: Study
Updated : 5 months, 1 week ago IST
A protein present in the brains of patients suffering from frontotemporal dementia (FTD) has been identified by an international team of researchers, which includes specialists from Indiana University School of Medicine. This finding opens up a new target for possible treatments for FTD.
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Smaller hippocampus associated with cognitive decline: Study
Updated : 2 years, 3 months ago IST
With the development of new medications that can target the amyloid-beta plaques in the brain that are an early symptom of Alzheimer's disease, new methods for determining whether memory loss and thinking issues are caused by Alzheimer's disease or another neurodegenerative disease are requi
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Graphene oxide nanoflakes lower toxicity of Alzheimer's proteins: Study
Updated : 2 years, 5 months ago IST
The collection of chemicals known as amyloid peptides is thought to be an early driver of Alzheimer's disease. These trigger cell death and are typically found in Alzheimer's patients' brains. Researchers at Chalmers University of Technology in Sweden have now demonstrated that after being t
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Study finds link between exercise-induced hormone irisin, Alzheimer’s dise
Updated : 2 years, 6 months ago IST
The first 3D human cell culture models of Alzheimer's disease (AD) that exhibit the two main symptoms of the disease—the formation of amyloid beta deposits followed by tau tangles—were created previously. Researchers are now using their model to examine whether the exercise-induced muscle ho
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Exercise-induced hormone irisin may help to reduce Alzheimer’s disease
Updated : 5 months, 1 week ago IST
searchers who previously developed the first 3D human cell culture models of Alzheimer's disease (AD) that exhibit two major hallmarks of the condition—the generation of amyloid beta deposits followed by tau tangles—have now used their model to investigate whether the exercise-induced muscle
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Researchers discover how specialized T cells in brain slow progression of
Updated : 2 years, 6 months ago IST
Alzheimer's disease, a neurological disorder characterised with progressive cognitive decline, including memory loss, affects up to 5.8 million Americans today. Protein aggregates, made up of beta-amyloid or other proteins, occur in the brains of Alzheimer's patients. These beta-amyloid plaq
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Japanese squirrels develop human hereditary diseases with ageing: Research
Updated : 2 years, 6 months ago IST
A team led by Dr Tomoaki Murakami of the Tokyo University of Agriculture and Technology discovered that fibrinogen A-chain amyloidosis, a previously unknown disease in animals other than humans, is common in Japanese squirrels (Sciurus lis). They compared the pathology of Japanese squirrels
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