Researchers have uncovered a gene that is overexpressed in mutated IDH1. Studies in human cells and a novel mouse model both show that this gene, called ZMYND8, plays a critical role in radiation resistance. When they knocked down the gene, the glioma cells became responsive to radiation tre
Researchers have uncovered a series of molecular interactions that may be crucial in preventing the spread of cancer cells. There is currently no effective therapeutic strategy to stop metastasis, which is the main cause of death from solid malignant tumours.
Researchers have uncovered novel candidate drug targets for non-alcoholic fatty liver disease (NAFLD) by using the latest technologies, including both single-nuclear sequencing of mice and human liver tissue and advanced 3D glass imaging of mice to characterize key scar-producing liver cells
Barrett oesophagus is a genetic mutation in the esophageal mucous membrane that can lead to esophageal cancer. If certain biomarkers, known as miDNA, which are extremely short DNA strands, are found in these tissue alterations, it could be an indication that this preliminary stage of esophag
A new study from researchers at Michigan State University underscores that there's still much to learn regarding how plants will function, and how nutritious they will be, as more carbon enters our atmosphere.
Human immunodeficiency virus 1, more commonly known as HIV-1, is known for its uncanny ability to evade the immune system. Scientists at Scripps Research and collaborators have now uncovered how our innate immune system, the body's first line of quick defence in attacking foreign invaders de
A new analysis has uncovered a potential link between higher prostate cancer risk and genetic variants associated with higher bloodstream levels of the cholesterol-transporting molecule lipoprotein A. Anna Ioannidou of Imperial College London, U.K., and colleagues present these findings in t
Researchers have uncovered a previously hidden heating process that helps explain how the atmosphere that surrounds the Sun called the "solar corona" can be vastly hotter than the solar surface that emits it.
BJP MP Rajyavardhan Singh Rathore on Monday took a swipe at the state government, claiming that the Ashok Gehlot government was not giving permission for CBI inquiry into the 'paper leak case' because it knows that 'big names' will be uncovered.
A group of scientists from North Carolina State University uncovered a jumping habit for insect larvae, and there is evidence that it occurs in a variety of species that haven't done it yet.
Investigators from the Smidt Heart Institute at Cedars-Sinai have identified how biological pacemaker cells--cells that control your heartbeat--can "fight back" against therapies to biologically correct abnormal heartbeat rates. The research also uncovered a new way to boost the effectivenes
A study supports the idea that some T cells that react to microbes also may react to normal human proteins, causing autoimmune disease. The findings promise to accelerate efforts to improve diagnostic tools and treatments for autoimmune diseases.