A novel cell signalling route was discovered by researchers at the Johns Hopkins Kimmel Cancer Centre that may one day be used as a therapeutic target for people with aggressive pancreatic cancer.
Immune Checkpoint Blockade, or ICB therapy, has become the gold standard for treating lung cancer because of its frequently successful results. High levels of the PD-L1 protein have served as the main indicator of a favourable response to treatment up until now
Isolated from other cells in a laboratory dish, tumour cells won't reveal their actual nature. Rice University researchers created an improved tumour model that houses osteosarcoma cells alongside immune cells known as macrophages inside a three-dimensional framework designed to simulate bon
A new weapon in the arsenal of cancer cells' treatment resistance, according to a study conducted by the Garvan Institute of Medical Research, is the ability for them to respond randomly to chemotherapy.
According to recent research led by the Garvan Institute of Medical Research, cancer cells have an inbuilt randomness in their capacity to respond to chemotherapy, which is another weapon in their treatment resistance toolbox.
Tumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spread. This limits glucose availability for immune cells and therefore dampens the body's anti-cancer immune response.
CAR T-cell therapy, a sort of cancer treatment in which the immune system's T cells are trained to attack tumour cells, was found to be effective in mice with ovarian cancer, according to a study.
According to a study, CAR T-cell therapy, a type of cancer treatment in which the immune system's T cells are trained to attack tumour cells, is successful in mice with ovarian cancer.
The source of tumour cell resistance to immunotherapy was identified by a recent study that examined the pancreatic cancer tumour microenvironment, and novel therapeutic approaches were developed as a result.
Researchers examine the local communication between endothelial cells and tumors cells and its effects on endothelial cell orientation. The approach uses co-cultured human umbilical vein endothelial cells and breast epithelial tumor cell lines to simulate the tumor-endothelial interaction. T
The study found protein is crucial in helping malignancies avoid immune attacks. The "fragile X mental retardation protein" (FMRP) is a protein that controls a network of genes and cells in the tumor microenvironment that help the tumor "hidden" from immune cells.