Why do some people get Alzheimer's while others don't? Even more perplexing, why do many people with toxic amyloid aggregates in their brains--a clear marker of Alzheimer's brain pathology--never get Alzheimer's-related dementias?
In the brains of people with Alzheimer's disease, the protein amyloid- clumps together. The eventual deposition of these aggregates as so-called plaques results in damage to the brain's blood vessels and tissue
The protein medin is deposited in the blood vessels of the brains of Alzheimer's patients along with the protein amyloid-b. Researchers from DZNE have discovered this so-called co-aggregation. They have now published their observation in the renowned journal Nature. "Medin has been known for
In Alzheimer's disease, the degeneration of brain cells is linked to formation of toxic protein aggregates and deposits known as amyloid plaques. Similar processes play an important role also in type 2 diabetes. A research team under the lead of the Technical University of Munich has now dev