A pioneering study undertaken by a Kumamoto University research team shed light on the crucial role of TRMT10A, a tRNA methylation enzyme, in sustaining brain function. The findings show how TRMT10A deficiency reduces specific transfer RNA (tRNA) levels in the brain, altering protein synthes
Neurons in the striatum, a part of the brain affected by Huntington's disease, are among the most severely affected. The degeneration of these neurons contributes to patients' loss of motor control, which is one of the disease's major symptoms.