Gene mutations are the cause of cancer. Tumor suppressors and oncogenes are the two main groups of these altered genes in cancer. Mutations in oncogenes can drive cell proliferation, pushing the gas pedal all the way to the floor, whereas mutations in tumour suppressor genes can cause tumour
St. Jude Children's Research Hospital scientists have developed an integrated, high-throughput system to better understand and possibly manipulate gene expression for the treatment of disorders such as sickle cell disease and beta thalassemia. The research appears today in the journal Nature