Now, a team led by Assistant Professor Yasuro Furuichi from Tokyo Metropolitan University have emerged with a key part of the puzzle. In previous work, they found that Musashi-2 (Msi2), a protein originally discovered in nerve cells, was also expressed in skeletal muscle tissue.
The study has described --in patients and animal model samples of type 2 diabetes-- a decrease in mitochondrial proteins that synthesize complex subunits of the respiratory chain. This decrease in proteins is associated with an increase in intracellular nitric oxide which, according to the r
A protein response that takes place at the cellular level as a result of ageing includes a balance between oxidants and antioxidants, low-grade inflammation, and is the cause of many medical conditions.