Search For "misfold"
Scientists find over 200 hidden proteins that may drive Alzheimer's: Study
Updated : 5 months, 1 week ago IST
A surprising new study has uncovered over 200 misfolded proteins in the brains of aging rats with cognitive decline, beyond the infamous amyloid and tau plaques long blamed for Alzheimer's.
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Graphene oxide nanoflakes lower toxicity of Alzheimer's proteins: Study
Updated : 2 years, 5 months ago IST
The collection of chemicals known as amyloid peptides is thought to be an early driver of Alzheimer's disease. These trigger cell death and are typically found in Alzheimer's patients' brains. Researchers at Chalmers University of Technology in Sweden have now demonstrated that after being t
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Study finds therapeutic target for removal of misfolded, unwanted proteins
Updated : 2 years, 5 months ago IST
When the UPS mechanism fails, cells engage in a compensatory protein clearance process known as "aggrephagy," in which protein aggregates are destroyed in a controlled manner by the cell.
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Study finds how misfolded alpha-synuclein protein helps to detect early Pa
Updated : 2 years, 11 months ago IST
According to a new study using technology created by a researcher at UTHealth Houston, the presence of a misfolded alpha-synuclein protein can be used to assess whether people have Parkinson's disease. This biomarker may open the door to the creation of improved diagnostic equipment and fres
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Researchers find misfolded alpha-synuclein protein help in early detection
Updated : 2 years, 11 months ago IST
Using technology created by a researcher at UTHealth Houston, a new study shows that the presence of a misfolded alpha-synuclein protein can be used to identify persons with Parkinson's disease. The discovery of this biomarker may lead to the creation of more accurate diagnostic equipment an
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Researchers give new insights into treatment of Alzheimer's disease
Updated : 3 years, 1 month ago IST
In Alzheimer's disease, a small protein known as amyloid beta misfolds to intermediates that aggregate into larger macromolecular structures known as fibrils and plaques
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Study: Sensor helps in early Alzheimer's detection of up to 17 years in a
Updated : 3 years, 7 months ago IST
Washington [U.S], July 25 (ANI): In the blood, a sensor finds indicators for misfolded protein biomarkers. This provides a chance to identify Alzheimer's before any symptoms appear. Investigators want to make it ready for the market.
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Peptide 'fingerprint' enables earlier diagnosis of Alzheimer's disease
Updated : 3 years, 7 months ago IST
Washington [U.S], July 21 (ANI): Neurodegenerative diseases like Alzheimer's disease or Parkinson's disease are caused by folding errors (misfolding) in proteins or peptides, i.e. by changes in their spatial structure. This is the result of minute deviations in the chemical composition of th
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Study: The astrocytic urea cycle in brain controls memory loss in Alzheime
Updated : 3 years, 8 months ago IST
Daejeon [South Korea], June 22 (ANI): The number of elderly people suffering from Alzheimer's disease has increased rapidly in recent decades. For a long time, scientists believed that misfolded aggregates of amyloid-beta protein accumulated and formed plaques in the brain, leading to memory
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Non-mutated Apolipoprotein E linked to dementia in the ageing brain: Study
Updated : 4 years, 1 month ago IST
Lexington (Kentucky) [US], January 27 (ANI): Dementia is one of those diseases for which no cure has been found till date. But research is ongoing, and now, in a recent study, researchers exploring dementia-related proteins in the brain identified Apolipoprotein E (ApoE) as a key misfolded p
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Scientists develop method to detect Alzheimer's at early stage
Updated : 6 years, 10 months ago IST
Washington D.C. [USA], May 4 (ANI): Researchers have developed a new two-tier method that can detect Alzheimer's disease at an earlier stage. Using the current technique, Alzheimer's disease can only be detected once the typical plaques have formed in the brain of the patients.
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