Researchers at the UCLA Health Jonsson Comprehensive Cancer Centre have identified a single protein, IGF2BP3, that links these two processes together in leukaemia cells. The protein alters how cells break down sugar, favouring a fast but inefficient energy pathway, while also modifying RNA t
Singapore, October 5: A new cell therapy, targeting CD7 on leukaemia cells, gives a potentially effective treatment for patients with T-cell acute lymphoblastic leukaemia (T-ALL) who have exhausted all standard treatment options. Published in the prestigious medical journal Nature Medicine o
This process of "programmed cell death" often goes wrong in cancer. Damaged mitochondria can also undergo a form of "self-eating" termed mitophagy that prevents them from sending "death signals."
After two years of chemotherapy treatment, nine out of ten children are cured. But some children have a more aggressive form of the disease. For example, children with a so-called Ikaros change in the DNA of their leukaemia cells have a greater risk of their disease coming back after treatme
Washington [US], July 1 (ANI): Researchers have discovered potential new drugs that target mitochondria in cancer cells. Their study in the journal Leukemia describes the compounds' potential for killing leukaemia cells when administered by themselves or in combination with other chemotherap