'Friends' actor Matthew Perry's death is under investigation by the Los Angeles Police Department and Drug Enforcement Administration (DEA) more than six months after he was found unresponsive at his residence in October 2023.
An international team of researchers has found that ketamine, being an NMDA receptor inhibitor, increases the brain's background noise, causing higher entropy of incoming sensory signals and disrupting their transmission between the thalamus and the cortex.
Ketamine, an established anesthetic and increasingly popular antidepressant, dramatically reorganizes activity in the brain, as if a switch had been flipped on its active circuits, according to a new study by Penn Medicine researchers.