Multi-time Premier League champions started with their two new signings, Tijjani Reijnders and Rayan Cherki, with their new skipper, Bernardo Silva, on the bench.
Ahead of the clash against Southampton in the Premier League, Manchester City manager Pep Guardiola provided an update about midfielder Kevin De Bruyne's injury on Friday.
Manchester City maintained their winning streak this Premier League season, mounting a sensational comeback against West Ham after going a goal down to eventually log full points with a 3-1 win at the London Stadium on Saturday.
"Manchester City are delighted to confirm the signing of Jeremy Doku from Stade Rennais on a five-year deal. Everyone at Manchester City is delighted to welcome Jeremy to the club and we all wish him well during his time here," the Premier League title defenders announced in a statement.