Living organisms have a knack for persisting in the face of challenges. For instance, when genes malfunction, organisms may be able to compensate by activating redundant genes with similar functions, called paralogs.
Each individual has an individual chemical fingerprint. The composition of small molecules in the blood, such as fats or sugars, determines how our body reacts to external influences, which diseases we are susceptible to and how severe an illness will be.
Using CRISPR techniques, the researchers removed parts of the yeast transcription machinery to systematically examine their role in regulating genes. Yeast and humans have mostly the same molecular machinery to regulate their genes, so yeast provides an excellent model for understanding gene
Washington [US], November 13 (ANI): Indiana University School of Medicine researchers investigated how the immune cells in the brain -- microglia -- relate to a gene mutation recently found in Alzheimer's disease patients.