According to a new multi-institutional translational study headed by Weill Cornell Medical experts, obesity may cause DNA damage in the breast tissue of women who have BRCA1 or BRCA2 mutations, potentially adding to breast cancer development in an already high-risk group.
Women who have BRCA1 or BRCA2 genetic abnormalities continue to have a significant chance of developing cancer after age 50, even if they have never been diagnosed with the disease. This is true even though these mutations are linked to a younger beginning of breast and ovarian cancer