Genetic interactions responsible for neuro disorders

Pregnancy loss affects up to 25 per cent of all pregnancies, with most miscarriages occurring in the first trimester and roughly half caused by genetic or chromosomal abnormalities. But when pregnancy loss occurs three or more times, identifying the underlying cause becomes significantly more challenging, and often remains unknown.

Hypertension may impair the brain far earlier than previously understood -- even before a measurable rise in blood pressure occurs -- according to a new preclinical study from Weill Cornell Medicine. The changes help explain why hypertension is a major risk factor for developing cognitive disorders, such as vascular cognitive impairment and Alzheimer's disease.

Women who experience hypertensive disorders of pregnancy (HDP) face significantly higher risks of cardiovascular complications, including heart attack, stroke, heart failure, and death, within five years of giving birth, according to a new study by Intermountain Health researchers.

Researchers discovered that early puberty or childbirth doubles women's risk for major diseases and accelerates ageing, while later timing offers protective benefits.

Gene editing technologies, such as those used in agriculture and de-extinction efforts, can be repurposed to provide what an international team of scientists describes as a breakthrough approach for restoring genetic variety and rescuing endangered species.

A new study suggested that obesity and anxiety may be connected through interactions between the gut and the brain.

It also provides evidence of eight instances in which introners have transferred between unrelated species in a process called 'horizontal gene transfer,' the first proven examples of this phenomenon.

People with excess weight are more likely to experience long-term neurological and mental health symptoms after Covid-19, including headache, vertigo, smell and taste disorders, sleep disturbance, and depression.

King's College London researchers have discovered a novel link between lipids and disorders affecting children's metabolism. This finding may provide an early warning system for ailments, including liver disease.

A study reveals that traumatic brain injury alters the small vessels in the brain, resulting in an accumulation of amyloid beta -- a hallmark of Alzheimer's disease. The findings suggest that vascular dysfunction could be an early driver in neurodegenerative disorders rather than being caused by neuronal damage.