Frequent heartburns up cancer risk in older adults

A low-fat vegan diet may support weight loss without the need to count calories, reduce portion sizes, or constantly battle hunger. In a 16-week clinical trial, participants following a diet centred on fruits, vegetables, grains and legumes consumed around 357 fewer calories per day, despite eating nearly the same amount of food overall.

Researchers are applying evolutionary theory to cancer by changing treatments before tumours have time to develop resistance. Mathematical models suggest that rapid, carefully timed switches between multiple therapies could improve cure rates.

Most adults can safely consume up to 400 mg of caffeine per day, equivalent to up to five 8-ounce cups of caffeinated coffee, without increasing cardiovascular risk, according to a new scientific statement released by the American Heart Association (AHA).

Scientists have identified a molecular switch that could help explain why colorectal cancer becomes more deadly. Researchers found that when levels of a gene-regulating factor known as GATA6 decline, cancer cells lose their normal identity and transform into highly adaptable, fetal-like cells that can spread through the bloodstream and form new tumours in the liver.

Researchers have uncovered a molecular "switch" that helps explain why exercise keeps ageing muscles healthy. By reducing levels of a gene called DEAF1, physical activity allows older muscles to clear out damage, repair themselves, and maintain strength.